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KCET Sat. Beauty and the Beast Freeform Sun. Cinema Paradiso Cinemax Thur. Dodsworth TCM Mon. BBC America Tues.

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The lifesaving chemotherapy and radiation treatments that allow patients to survive cancer can also result in a lifetime of side-effects, including male infertility. Infertility in male cancer survivors is thought to primarily result from killing of the spermatogonial stem cells SSCs responsible for producing spermatozoa since SSCs turn over slowly and are thereby sensitive to antineoplastic therapies. We previously demonstrated that the cytokine granulocyte colony-stimulating factor G-CSF can preserve spermatogenesis after alkylating chemotherapy busulfan.